No significant differences were found for sex, body weight, age, breed distribution, minimum stage, substage, presence of B‐symptoms, pretreatment with corticosteroids for <14 days before commencing chemotherapy, presence of anemia, presence of hypercalcemia, and extranodal involvement between the CHOP‐19 and CHOP‐25 groups. Here, DDIT3 is linked to anemia.