CAV1 and glaucoma: For example, the nodal, membrane raft pathway includes the caveolin genes, Cav1 and Cav2, which are functionally implicated in intraocular pressure modulation and glaucoma (Enyong et al., 2022; Elliott et al., 2016) as well as the caveolae-related genes, Cavin2 and Cavin3, with roles in regulating the formation of caveolae (Kovtun et al., 2015; Figure 7D).