INS and hepatocellular carcinoma: Therefore, in this study, combined with network pharmacological analysis and experimental verification, human hepatocellular carcinomas (HepG2) cells were induced by free fatty acid (FFA) to build an insulin resistance model, to elucidate the molecular mechanism of BBR regulating PPAR signaling pathway to improve insulin resistance, and providing a new therapeutic idea for the prevention and treatment of type 2 diabetes.