BCL2 and asthma: In an ovalbumin-lipopolysaccharide (OVA-LPS)-induced animal model of asthma, bronchioalveolar epithelial cells in the lungs were found to undergo apoptosis through the activation of p38 MAPK, inhibition of Bcl-2, and induction of B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) (21).