IL6 and coronary artery disorder: Additionally, the Mangano et al. (2013) study clarified that while the administration of soy protein (18 g/d) and isoflavone tablets (105 mg/d isoflavone aglycone equivalents) to 131 healthy, ambulatory older women was effective in reducing inflammatory markers (IL-6), it did not improve serum lipid levels, which are thought to be a critical risk factor in coronary heart disease (CHD).