The first steps in the management of NAFLD include adopting a healthy lifestyle like eating a nutritious diet, avoiding an energy-dense carbohydrate-rich diet, lowering food portions, and regular physical exercise to reduce weight and several hypoglycemic agents like thiazolidinedione and sodium-glucose cotransporter-2 blocker can be part of the management. Here, SLC5A2 is linked to metabolic dysfunction-associated steatotic liver disease.