Table 1 delineates these obstacles and proposes potential solutions. Initiatives such as implementing universal health coverage, developing national cancer care plans to guarantee access to essential diagnostic and treatment resources and establishing comprehensive population-based cancer registries are critical for strengthening healthcare systems in LMICs. These registries will provide valuable data on disease burden and facilitate targeted interventions tailored to specific populations, including individuals with BRCA1/2 germline mutations. The gene discussed is BRCA1; the disease is cancer.