Factors that were found to be associated with disease activity in patients with rheumatoid arthritis (RA) according to the Disease Activity Score 28 (DAS28) include age, level of erythrocyte sedimentation rate (ESR), visual analog scale of pain (VAS), and C-reactive protein (CRP) (Kurniari and Kambayana, 2021; Abdelnaby et al., 2021; Al-Shamali et al., 2021). This evidence concerns the gene CRP and rheumatoid arthritis.