The EGFR in A431 cells, the squamous cell carcinoma cell lines, are glycosylated by A antigen, as well as Lewis Y antigen, another product of FUT1 that is mostly expressed in cancer cells, and these sugar structures influence the binding of the EGF to its binding site on the receptor [20, 25–44]. The gene discussed is EGFR; the disease is squamous cell carcinoma.