IFNG and vitiligo: On the basis of these findings, researchers have shown that the location preference of vitiligo is associated with the ability of fibroblasts at different sites to respond to interferon gamma (IFN-γ), and as the only skin cells capable of recruiting and activating their own active CD8+ T cells, the ability of these cells to recruit active CD8+ T cells via CXCL9/CXCL10-CXCR3 correlates with IFN-γ (Xu et al. 2022).