Conversely, non-T cell-inflamed MIUBC frequently exhibits activations in the beta-catenin, peroxisome proliferator-activated receptor-gamma (PPARγ), and fibroblast growth factor receptor 3 (FGFR3) pathways.748 For successful responses to anti-PD-L1 therapy in mice, the presence of “sufficient” T cell infiltration at the tumor site is considered more crucial than variations in PD-L1 expression levels, laying the foundation for potential strategic developments.421. The gene discussed is FGFR3; the disease is neoplasm.