EGFR and liver cancer: For instance, in an in situ VX2 liver cancer model, monitoring through magnetic resonance imaging (MRI) revealed that locally delivered immunomodulatory nanocomplex microspheres (IMM-MS) via hepatic artery intervention selectively targeted liver tumors, significantly increasing NK cell infiltration at the site of liver tumors.881 Trivalent nanoparticles, referred to as a-EGFR/a-CD16/a-4-1BB NPs, have shown promising capabilities in recruiting and triggering NK cells towards attacking tumor cells with elevated levels of EGFR.