TSHZ3 and Horseshoe kidney: The other anomalies in TSHZ3 variant carriers, i.e., kidney (hypo)dysplasia, VUR, ureteropelvic junction obstruction, duplex kidney, posterior urethral valves, kidney cysts/cystic kidney dysplasia, and horseshoe kidney, were not present significantly more frequently than in non-carriers (Fig. 2L).