ZCCHC24 and neoplasm: To test this in vivo, we added siRNAs against ZCCHC24 together with JQ1 treatment to subcutaneously grafted MDAMB231 or PDX cells and found that the dual use of JQ1 and siRNA against ZCCHC24 had additive effects in suppressing tumor growth in both models compared with single treatments (Fig. 6A).