In addition to pathogenic mutations in well-established PD-related genes (LRRK2, PRKN, PINK1, SNCA, PLA2G6 and GBA1), we identified pathogenic mutations in genes that have been reported to present as levodopa-responsive parkinsonism but typically present with alternative or atypical phenotypes. The gene discussed is PRKN; the disease is Parkinsonism.