Since transient blockade of type I IFN signaling was shown to render WT mice susceptible to ZIKV or DENV infection [49,53], without altering T cell responses to antigenic peptides [55], we treated mice with 2mg of the anti-IFNAR antibody MAR1-5A3 one day prior to infection at day 36 with 103 pfu of ZIKV or 106 pfu of DENV2., and quantified viremia from day 1 to 4 after infection. This evidence concerns the gene IFNAR1 and infection.