ECM1 and triple-negative breast carcinoma: At the same time, GSE128099 data set was analyzed and in the triple-negative breast cancer cell line supplemented with gemcitabine, four hub genes showed higher expression than previously, among which CERCAM (P = 0.00029), ECM1 (P = 0.0072) and KLF10 (P = 0.027) were statistically significant, while HGF showed an increasing trend but no statistical significance (Fig 9C).