Secondly, FreeViz analysis of the CD57+CD56dim NK cell subset demonstrated that expression of CD8 contributed further to the separation of mature CD57+ NK cells that distinguished stable from intermittent remission (Figure 1C), such that the proportion of CD8+CD57+ NK cells was significantly increased in stable RA remission (Figure 1D). The gene discussed is CD8A; the disease is rheumatoid arthritis.