Several studies have found an association between two promoter genetic polymorphisms rs764522 (−1444C/G) and rs3087465 (−834A/G) in TGFβR2 and some diseases, such as abdominal aortic aneurysm,51 and end-stage renal disease.52 The gene discussed is TGFBR2; the disease is stage 5 chronic kidney disease.