CCL25 and non-small cell lung carcinoma: To evaluate accumulative effect of the three independent SNPs on NSCLC survival, we combined their unfavorable genotypes (i.e., LRRC8C rs10493829 TT, OAS2 rs2239193 AG+GG, and CCL25 rs3136651 TT) into a genetic score that was used to categorize all NSCLC patients into four groups (i.e., 0, 1, 2, and 3) by the number of their unfavorable genotypes (NUG).