Furthermore, co-culturing IFN-γ-overexpressing BM-MSCs with human chronic myelogenous leukaemia (CML) K562 cells resulted in strong inhibition of leukemic cell apoptosis and cell proliferation, along with the induction of G1 phase cell cycle arrest (61). The gene discussed is IFNG; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.