Immunohistochemistry study showed reduced infiltration of FoxP3+ Treg cells and increased numbers of CD4+ T-cells and cells expressing interleukin-12-beta-2 receptor (IL-12Rβ2+) and interleukin-24 (IL-24+) in the tumour from γT3-treated animals. The gene discussed is IL12RB2; the disease is neoplasm.