In another study, daily supplementation of γT3 in a syngeneic mouse model of BC showed reduced tumour size, an increase in the CD4+CD127+ T-cell population, and a decrease in the Treg population alongside upregulation of tumour suppressor genes such as the mitogen inducible gene 6 (MIG6) and Cadherin-13 [31]. This evidence concerns the gene CDH13 and neoplasm.