SLC38A7 and breast carcinoma: Furthermore, the inhibition of the amino acid transporter LAT1 using the compound KYT0353 (also known as JPH203) in the highly metastatic breast cancer cells, MDA-MB-231, led to a decreased distribution of peripheral lysosomes (Fig. 6B) and marked reduction in cell migration as early as 2 hours of treatment (Fig. 6C).