BRD2 and polycystic ovary syndrome: In laboratory studies, serum FSH concentrations and the volume of the corpus luteum were shown to decrease in the PCOS + Ami group (amitriptyline-treated rats) compared to the PCOS group (amitriptyline-no-administered rats); however, amitriptyline did not affect the morphological and biochemical changes caused by PCOS in the ovarian tissues and degenerative areas.