Additionally, the investigation into the gene expression patterns of Bax and Bcl-2 in MCF-7 and A-375 cells after their exposure to both nanosystems unveiled an elevation in their ratio of Bax/Bcl-2 (>1), indicating a significant increase in apoptosis in the treated cancer cells.197 Current findings highlight the potential of polymeric alginate nanoparticles as nanocarriers for application against breast and melanoma cancers. The gene discussed is BAX; the disease is melanoma.