Next, we assessed if the migratory behavior of CD4 or CD8 T cells was any different and found that increase in total T cell migration in the presence of the MDMs and tumor cells was due to a comparable increase in both subsets with a 3 to 4-times fold-over change in Tri-culture over matched monocultures in the context of both tumor cell lines (Fig. 2D,E). This evidence concerns the gene CD8A and neoplasm.