Low haemoglobin, abdominal mass, abdominal pain, loss of appetite, chest signs, dysphagia, hypoalbuminaemia, iron deficiency anaemia, jaundice, leucocytosis, lymphadenopathy, nausea, pelvic mass, raised alkaline phosphatase, raised C reactive protein, raised erythrocyte sedimentation rate, reflux, thrombocytosis, venous thromboembolism, vomiting. The gene discussed is CRP; the disease is thrombocytosis disease.