We found evidence for clinical features and abnormal blood test results that were predictive of cancer in combination with unexpected weight loss not previously reported: loss of appetite, abdominal mass, back pain, bloating, chest signs, dyspepsia, fatigue, nausea, reflux, pelvic mass, venous thromboembolism, raised alkaline phosphatase, low albumin, and a raised white cell count. This evidence concerns the gene ALB and venous thromboembolism.