It has been further shown that blocking OTR in the mPFC of postnatal rats by an OTR antagonist delayed the retrieval of pups and reduced the number of pups retrieved by rats, impaired the care of pups, decreased the latency to attack intruders, increased the number of attacks, and increased anxiety in postnatal rats but had no effect on the level of anxiety in virgin rats (Sabihi et al., 2014). This evidence concerns the gene OXTR and Anxiety.