miR-214-3p has been implicated in regulating cellular processes of HCC and is associated with patients’ prognosis.15 Additionally, miR-214-3p has been reported to mediate the enhancing effect of several lncRNAs, including LINC00665, HCG18, and HOXA11-AS on the development of HCC.16-20 With the employment of online databases, the target relationship between POLR2J4 and miR-214-3p was revealed with several binding sites. This evidence concerns the gene HCG18 and hepatocellular carcinoma.