PNPLA3 and steatosis: Similarly, data from a cohort of about 4000 subjects from the Study of Health in Pomerania and with the availability of PNPLA3 genotyping and ultrasound assessment of steatosis, did not report any link between PNPLA3 rs738408 C > G variant and extrahepatic cancers in the entire cohort, while showing a protective effect (adjusted HR 0.39) only in females without steatosis [84].