To validate the function of cGAS‐STING‐type I interferon pathway and CD8+ T cells in the combination therapy in vivo, we then carried out an additional experiment by treating tumor‐bearing mice with IFNAR1 or CD8 blocking antibodies, the efficacy of the combination therapy was significantly impaired by IFNAR1 or CD8 neutralization. This evidence concerns the gene CD8A and neoplasm.