SHBG and metabolic syndrome: Though it is well documented that the measurements of SHBG are used to predict free androgen levels in patients afflicted by excessand over exuberant androgen exposure, it needs to be realized that broader utility rests with SHBG in assessing the risk of developingendocrine diseases and more specifically in the realms of MetS with concomitant IR.SHBG gene polymorphism (rs1799941) has been linked toMetS in children and adolescents [47].