MCL1 and Miyoshi myopathy: However, MM cells with high Mcl-1 expression are less sensitive to venetoclax (Punnoose et al., 2016a), and Mcl-1 downregulation can increase sensitivity and overcome resistance (Pandey et al., 2013; Tse et al., 2008; Cory and Adams, 2005; van Delft et al., 2006; Chen et al., 2007; Lucas et al., 2012).