Age, sex, BMI, inflammation (GOT, GTP, ALK, amylase, BUN, UA, creatinine, homocysteine), lifestyle factors (past smoker, drinking habits and betel nut consumpfion), iron status (hemoglobin, IDA) and self-reported family health history of chronic diseases (hyperlipidemia, fatty liver disease, hypertension, diabetes mellitus). This evidence concerns the gene ALK and Hypertension.