These autoantibodies are divided in two groups, namely myositis-specific autoantibodies (MSAs), which are unique to IIM and usually mutually exclusive to one another, or myositis-associated autoantibodies (MAAs) which can occur also in other connective tissue diseases (CTDs) or overlap syndromes, but are not specific for myositis [2,3]. Here, MAPKAPK5-AS1 is linked to myositis disease.