There were significant correlations between the abundance of several species in the standard dose DMB group and a variety of outcomes, as shown in Figure 3A. The abundance of Streptococcus genus, particularly species of Streptococcus thermophilus, Streptococcus pneumoniae, Streptococcus dysgalactiae and Streptococcus agalactiae, correlated negatively with the concentration levels of TNF-α in patients with cancer. Here, TNF is linked to cancer.