TFE3 and neoplasm with perivascular epithelioid cell differentiation: Compared to TFE3-rearranged PEComas occurring in other sites (especially the uterus, bladder, and soft tissues), those in the kidney arise less frequently in females (60% versus 73%), in younger patients (second versus fourth decade of life), and less frequently carry the NONO::TFE3 rearrangement, which is instead the second most common alteration (17%) behind SFPQ/PSF::TFE3 in extrarenal TFE3-rearranged PEComas [85].