NUMA1 and neoplasm: Figure 6 shows extensive positive staining for α-SMA in both models. NuMA was used as a marker for human cells. Tumors infiltrated by mouse cells were observed as early as 12 days post-injection (see Supporting Information Figure S5). The detection of α-SMA and NuMa in sequential tumor sections revealed that tumor-infiltrating mouse cells are α-SMA-positive. PanC-1 cells in monolayer are α-SMA-negative, as confirmed by western blotting (Figure 6C).