These pieces of evidence suggest the greater acquisition of SASP in 28Si compared to the γ-ray or control group in the tumor as well as normal tissue (Figure 7C,D and Figure S3A,B), whereas a lower level of Lgr5-GFP expression was observed after irradiation in normal as well as in tumor tissue (Figure 7D, Figures S2B and S3B). The gene discussed is LGR5; the disease is neoplasm.