PALB2 and familial pancreatic carcinoma: Although the spectrum of pathogenic PALB2 variants is diverse, studies on patients with breast, ovarian, and pancreatic cancers have identified the top five most frequently reported pathogenic variants as c.509_510del;p.(Arg170IlefsTer14), c.3113G>A;p.(Trp1038Ter), c.1592del;p.(Leu531CysfsTer30), c.172_175del;p.(Gln60ArgfsTer7), and c.1240C>T;p.(Arg414Ter), which account for 57.3% of all cases [10].