CD44 and breast carcinoma: In another study, single-cell RNA-sequencing revealed that a cluster of breast cancer cells from mammoplasty samples with aldehyde dehydrogenase activity (ALDH+) express high levels of the epithelial genes KRT7, KRT8, EPCAM, and CDH1 and high levels of the mesenchymal genes IL6, CD44, TM4SF1, and VIM [13].