AIF1 and mesenchymal cell neoplasm: For instance, Kaffes et al. [46] classified primary and recurrent tumors into several tumor subtypes and found that high Iba1 levels conferred distinct prognostic implications contingent upon a pro-neural (worse prognosis with increased Iba1) or mesenchymal tumor (improved prognosis with increased Iba1) subtype (Table 1).