TP53 and adenoma: The frequency of p53 expression in UCAN has been reported to be 0–31%, 59–80%, and 57–91% for LGD, HGD, and CAC, respectively, and the frequency of p53 expression in non-UCAN to be 4–22% and 55–61% for adenoma and CRC, respectively; the frequency of p53 expression in UCAN is known to be higher than in non-UCAN [37,38,39,40].