TP53 and neoplasm: Previous studies have reported that the frequency of TP53 mutations in colitis-associated neoplasia were 33%, 63%, and 80–89% in LGD, HGD, and CAC, respectively [41,42,43,44], and that the TP53 mutation frequency in non-UCAN was 52–61% [41,42,43], even in carcinoma.