A study showed that the SNP of rs3783605 occurs at the Proto-Oncogene 2 Transcription Factor (ETS2) binding site and, as a result, could have a role in the etiology of diseases linked to VCAM-1 dysregulation such as multiple sclerosis, asthma, atherosclerotic lesions, thromboembolic disorders, multiple myeloma, insulin-dependent diabetes mellitus, and breast cancer [25]. Here, ETS2 is linked to plasma cell myeloma.