EIF6 and hepatocellular carcinoma: Furthermore, eIF6 has been shown to play a vital role as a driver and prognostic marker in multiple cancers, including breast cancer [29], colorectal carcinoma [162], ovarian adenocarcinoma [58], non-small-cell lung cancer [163], lung adenocarcinoma [164], esophageal carcinoma [165], hepatocellular carcinoma, and glioblastoma [166].