CD274 and neoplasm: Since PD-L1 TPS, IC, and CPS indexes are described as the proportion of the whole tumour area occupied by PD-L1-positive tumour or immune cells regardless of department of these cells, we further analyzed specifically PD-L1+ lymphocyte distribution in TME (tumour islets and stroma) in 10 most representative high-power fields (HPFs ×400 magnification) per tissue section in all 72 cases, including those with negative PD-L1 expression evaluated by TPS, IC, and CPS.