Long COVID exhibits similarities with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS), however [435,458,459,460,461,462,463,464], so it is of interest that thrombospondin and platelet factor 4 are both raised in the plasma of individuals with ME/CFS [463]. The gene discussed is PF4; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.