In the cases of RET, CCDC6, MET, EML4, and ALK, a similar clustering was observed with each other and the type of thyroidectomy performed (near-total thyroidectomy, lobectomy, partial surgery with or without completion), the indication of radioiodine (RAI) therapy, a smaller than 1 cm tumor size in diameter during preoperative diagnostics with imaging techniques, a medical history of Hashimoto’s disease and hypothyroidism, as well as a family history of any thyroid-related disease. The gene discussed is CCDC6; the disease is hypothyroidism.