Jun Chen and coauthors reported a nano-size “artificial necroptotic cancer cell” (αHSP70p-CM-CaP) as a flexible vaccine platform for efficient lymph mode trafficking, multi-epitope-T cell response, IFN-γ-expressing CD8+ T cells and natural killer group 2 member D positive (NKG2D+) NK cell expansion [93]. The gene discussed is IFNG; the disease is cancer.