The SNP rs7946 (+5465G → A) in PEMT, encoding a substitution of valine with methionine at position 175 (V175M) in PEMT, is linked to an augmented risk of developing NAFLD, including NASH, especially in non-obese East Asian individuals [50,51,52,53]. This evidence concerns the gene PEMT and metabolic dysfunction-associated steatotic liver disease.