Apart from the increased levels of canonical activators of lipid uptake and adipogenesis PPAR α and γ mRNA observed in the colon of rats receiving chitin–glucan and L. acidophilus NCFM compared to the control animals with colitis, our study did not evaluate the influence of chitin–glucan supplementation on the composition of the gut microbiota and cardiometabolic profiles of animals with long-lasting colon hypersensitivity. The gene discussed is PPARA; the disease is colitis.